Houston, TX – October 23, 2025
It’s a heavyweight interconference showdown deep in the heart of Texas as the Houston Texans (4–2) welcome the San Francisco 49ers (5–1) to NRG Stadium for a Week 8 clash broadcast nationally on FOX.
Both teams mirror each other — fast, physical, and driven by young quarterbacks who have become faces of their franchises. With C.J. Stroud commanding Houston’s offense and Brock Purdy leading San Francisco’s precision attack, this one promises fireworks from the first snap.
📺 WATCH / STREAM
National Broadcast: FOX
Kickoff: Sunday, October 26 — 1:00 p.m. ET / 12:00 p.m. CT
Pregame Coverage: Begins at 12:30 p.m. ET
Postgame Analysis: Immediately following the final whistle
Broadcast Team (FOX):
Play-by-Play — Kevin Burkhardt
Analyst — Greg Olsen
Sideline Reporters — Erin Andrews & Tom Rinaldi
Streaming Options:
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FOX Sports App – stream live with participating TV provider
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NFL+ (Mobile Only) – live local & primetime games + full replays
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FuboTV / YouTube TV / Hulu + Live TV – FOX coverage nationwide
🏟 GAME INFO
Matchup: San Francisco 49ers (5–1) at Houston Texans (4–2)
Venue: NRG Stadium – Houston, Texas
Kickoff: 1:00 p.m. ET / 12:00 p.m. CT
The 49ers enter Week 8 fresh off a bye and reloaded with star power. Quarterback Brock Purdy
returns to lead an offense built around do-it-all back Christian McCaffrey, a reliable veteran in Jauan Jennings, and a steady tight-end force in George Kittle. With Trent Williams
and Aaron Banks anchoring the trenches and new addition Ricky Pearsall stretching the field, Kyle Shanahan’s unit remains a model of balance and efficiency.
On defense, San Francisco leans on its retooled front:
Bryce Huff, Yetur Gross-Matos, and Jordan Elliott headline a rotation that still creates havoc even without Nick Bosa (IR). Linebackers Dee Winters and Luke Gifford play behind an active interior, while the secondary — featuring
Deommodore Lenoir, Renardo Green, and safety Ji’Ayir Brown — looks to contain Houston’s speedy receivers.
The Texans counter with a rapid-fire offense built around C.J. Stroud, who has quickly developed chemistry with
Nico Collins, Braxton Berrios, and tight end Dalton Schultz. Running backs Nick Chubb and Dameon Pierce share the load behind a revamped line anchored by Trent Brown
and Laken Tomlinson.
Defensively, Houston is young and hungry. Will Anderson Jr., Denico Autry, and Sheldon Rankins form a powerful front, while linebackers Azeez Al-Shaair and E.J. Speed
track sideline to sideline. The secondary — led by Derek Stingley Jr., Jalen Pitre, and rookie Calen Bullock — faces its biggest test yet against Shanahan’s play-action scheme.
🎧 LISTEN
Texans Radio Network
Live Game Coverage: 12:00 p.m. CT
Pregame: 10:30 a.m. CT
Postgame: Immediately after the game
Houston Stations: SportsRadio 610 AM / 100.3 FM – Flagship home of Texans broadcasts
Bay Area Stations: KNBR 680 AM / 104.5 FM – 49ers Radio Network
Streaming Audio: Texans.com | Texans Mobile App | 49ers Mobile App
(Geo-restrictions may apply)
SiriusXM Channels: 49ers Feed 227 | Texans Feed 385
💰 BETTING SNAPSHOT (via BetMGM)
| Category | 49ers | Texans |
|---|---|---|
| Spread | -4.5 (-110) | +4.5 (-110) |
| Moneyline | -220 | +180 |
| Over/Under | 46.5 points (Over -110 / Under -110) |
San Francisco enters as the favorite, but Houston’s home-field edge and Stroud’s accuracy could turn this into a down-to-the-wire finish.
⚙️ KEY STORYLINES
Can Brock Purdy handle Houston’s relentless front four?
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Will C.J. Stroud stay sharp against San Francisco’s disguised zone pressures?
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Can Christian McCaffrey find daylight behind Trent Williams and Aaron Banks?
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Will Will Anderson Jr. disrupt the 49ers’ timing early and set the tone for the Texans?
🏈 SUMMARY
Two young quarterbacks. Two disciplined coaches. One national stage.
The Texans look to defend home turf and cement their AFC status, while the 49ers seek to prove that their dominance travels anywhere.
Kickoff: Sunday, October 26 — 1:00 p.m. ET on FOX and the FOX Sports App.
Red and Gold meets Battle Red — the future of football is now. 🔥
